It is said that in ancient times anyone who found rare Linghzi never revealed place and kept it a secret of health, longevity and wealth. The Japanese revered herb as ‘God’s Herb’ where it is known as Reishi.

Lingzhi in medicine was considered so auspicious that its medical efficacy has been attested to in oldest Chinese medical text (over 2,000 years old). The book, which is known in Japan as "Shinnoh Honsohkyo", is now accepted as being original textbook of Oriental medical science. In it, 365 kinds of medicines are classified and explained. Ganoderma is classified as “Superior Herb” or "God's Herbs" and they are for perpetual youth and longevity. The book states that for "superior" medicines, any amount can be taken as desired on a continuous basis with no unfavorable effects. Of superior medicines listed in text, Lingzhi was rated number one. You can see how important and powerful Lingzhi was considered in ancient times. It achieved its ranking in Chinese text not because of its symbolic importance as a good omen but because of its medicinal properties. Centuries ago, Lingzhi was said to be a medicine that would grant you eternal youth and longevity.

But after 2,000 years, Lingzhi has jumped into spotlight as a specific medicine for cancer. This must be a bitter irony for those in modern medical profession who discounted herbal remedies and oriental medicine as being “old wives' tales". The families of many cancer patients who have received a diagnostic "death sentence" now seek reishi as only way left for them.

The Linghzi Mushrooms grows only on old tree barks with specific conditions difficult to replicate.

Till 1971 herb was so rare that it was hardly sited except in mountainous areas. Many researchers had attempted to plant Ganoderma artificially but failed. Till in 1971 directed by Naoi Department of Agriculture and Professor Zenzaburo Kasai, Kyoto University made a breakthrough in its cultivation.

The mini-micrografting procedure involves removing donor tissue with a multi-bladed knife. The tissue is then cut into smaller pieces using direct visualization; therefore, instead of using a microscope to cut tissue, a surgeon might use help of a regular ruler.

The size of grafts is dependent upon decision of surgeon and patient who can choose to cut micrografts (1-2 hairs) or minigrafts (3-6 hairs). When cutting grafts, excess skin is not trimmed thereby making wounds larger than necessary upon implantation.